Risk of death from cardiovascular disease and chronic bronchitis determined by place of birth in England and Wales
Osmond, C.; Barker, D.J.; Slattery, J.M.
Journal of Epidemiology and Community Health 44(2): 139-141
1990
ISSN/ISBN: 0143-005X PMID: 2370502 DOI: 10.1136/jech.44.2.139Document Number: 368488
The aim of the study was to examine the relation between place of birth within England and Wales (UK) and cause of death. The study was a population survey using data provided by the Office of Population Censuses and Surveys which, for a trial period between 1969 and 1972, coded place of birth on death certificates. The survey involved almost 2 million people who died in England and Wales between April 1969 and December 1972. Persons born in northern counties and industrial towns, and in Wales, had increased risk of ischaemic heart disease and stroke, which persisted whether or not they had moved to other parts of the country. A low risk of cardiovascular disease amnog people born in and around London went with them when they moved. People born in cities and large towns had an increased and persisting risk of chronic bronchitis. These findings are evidence that past geographical differences in fetal and infant growth, and in exposure to respiratory infection in early childhood, partly determine today's differences in adult death rates.