Prevalence of the antibody of hepatitis C virus in HBsAg negative patients with chronic liver diseases: children, prostitutes, and homosexuals

Vetencourt, R.; de Armas, J.; Vetencourt, M.

G.E.N 44(4): 349-352

1990


ISSN/ISBN: 0016-3503
PMID: 1967088
Document Number: 366922
We present the results of the determination of hepatitis C virus antibody, recently discovered on a group of 34 patients with chronic liver disease, divided in: a) 23 patients with cirrhosis. b) 8 with protracted hepatitis. c) 2 with steatosis of unknown origin++. d) One patients with hepatocellular carcinoma. Another group examined was integrated by persons of promiscuous sexual activity (15 prostitutes and 14 homosexuals). Finally we included 20 children chronically infected with VB. In the 23 patients with cirrhosis, the VB markers (HBsAg and anti-core were negative in 18 and 5 were only anti-core positive; anti-HCV was positive in 3 of the 18 VB negative (16.6%) and in one of the 5 with anti-core positive (20%), that represents a total of 4 cases anti-HCV positive (17.3%). 5 of the 8 patients with protracted hepatitis were virus B and A negative and 4 of them were anti-HCV positive (80%), 3 of which had parenteral infection. The 15 prostitutes and the 14 homosexuals were negative for the anti-HCV, as well as the 20 children chronically VB infected. Our result of the determination of anti-HCV in cryptogenetic cirrhosis (17.3%) is similar that reported in USA (> 20%) and very much lower than of the Italian group (80%). Meanwhile we found a high incidence in protracted hepatitis (80%) with parenteral infection.

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