Adverse effects of antiepileptic drugs on the nervous system

Opavský, J.

Acta Universitatis Palackianae Olomucensis Facultatis Medicae 128: 75-92


ISSN/ISBN: 0301-2514
PMID: 2149804
Document Number: 366777
The paper provides a brief account on undesired antiepileptic drug effects on the nervous system and implies both the typical pictures and also the less common symptoms of intoxications promoted by these drugs. It describes cognitive dysfunctions, various disorders of psychic functions including paradoxical reactions, emotivity and affectivity disorders, hyperkinestias and dyskinestias, peripheral neuropathies and other undesired effects. Individual groups of antiepileptic drugs are referred. Attention is also paid to some interactions and risk antiepileptic drug combinations.

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