Acicular ichthyosis (the Curth-Macklin type)
Aĭvazian, A.A.
Vestnik Dermatologii i Venerologii 9: 64-67
1990
ISSN/ISBN: 0042-4609 PMID: 2284863 Document Number: 366484
It is suggested that the double-nucleus phenomenon in the epidermis in type Curth-Macklin [correction of Kurt-McLean] acicular ichthyosis is due to cytokinesis-controlling gene mutation. Other hereditary dermatoses associated with needle-like hyperkeratosis appear to be a heterogenic group not necessarily involving the formation of double-nuclear cells. The essence of double-nucleus phenomenon and morphogenesis of acicular ichthyosis are disputable at present.