Acicular ichthyosis (the Curth-Macklin type)

Aĭvazian, A.A.

Vestnik Dermatologii i Venerologii 9: 64-67


ISSN/ISBN: 0042-4609
PMID: 2284863
Document Number: 366484
It is suggested that the double-nucleus phenomenon in the epidermis in type Curth-Macklin [correction of Kurt-McLean] acicular ichthyosis is due to cytokinesis-controlling gene mutation. Other hereditary dermatoses associated with needle-like hyperkeratosis appear to be a heterogenic group not necessarily involving the formation of double-nuclear cells. The essence of double-nucleus phenomenon and morphogenesis of acicular ichthyosis are disputable at present.

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