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Determination of human serum phospholipase A2. Comparison of two methods

Märki, F.; Pignat, W.; Steinbrückner, B.; Hoffmann, G.E.

Journal of Clinical Chemistry and Clinical Biochemistry 28(8): 543-544

1990

ISSN/ISBN: 0340-076X
PMID: 2258714
Document Number: 365506
A photometric assay for serum phospholipase A is compared with a radiometric assay specific for phospholipase A2. The methods show a high correlation. The increased phospholipase A activity in sera of patients with inflammatory and non-pancreatic necrotizing diseases is attributable to a neutral-active, calcium-sensitive phospholipase A2 but not to pancreatic phospholipase A2. Phospholipase A1 did not seem to contribute significantly to the overall activity of phospholipase A.

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