Titration and stability tests for antimeasles vaccine
Ayala-González, M.
Boletin Medico del Hospital Infantil de Mexico 47(7): 512-515
1990
ISSN/ISBN: 0539-6115 PMID: 2206418 Document Number: 364756
Production and quality of the vaccines, are important activities in the prevention of measles disease. Edmonston-Zagreb measles vaccine is the main strain attenuated virus distributed in México. In order to evaluate the titer of Edmonston-Zagreb and Schwarz vaccines, 50% tissue culture infective dose (TCID50/0.5 mL) and plaque-forming units (PFU) are performed in the National Laboratory of Public Health. Furthermore PFU is a method used in the stability vaccine test. Validation criteria are described in this paper.