Group a beta-hemolytic streptococcal bacteremia and intravenous substance abuse. a growing clinical problem?

Lentnek, A.L.; Giger, O.; O'Rourke, E.

Archives of Internal Medicine 150(1): 89-93

1990


ISSN/ISBN: 0003-9926
PMID: 2404484
Document Number: 364749
Over an 18-month period, the incidence of group A beta-hemolytic streptococcal bacteremia rose from an average of 2.5 per 10,000 patient discharges to 17.9. A retrospective analysis was performed comparing patients with group A beta-hemolytic streptococcal bacteremia during this 18-month period with those who presented over the preceding 36 months. Most of the increased incidence was attributable to individuals hospitalized with a diagnosis of drug addiction who had concomitant soft-tissue infection, although the absolute number of hospitalized drug addicts did not change during this interval. No common or distinctive group A streptococcal serotypic patterns were discovered. This experience suggests that group A beta-hemolytic streptococcal bacteremia and soft-tissue infection may present in epidemic fashion among parenteral drug addicts in the absence of a common source.

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