Treatment options for recurrent lymphomas
Fisher, R.I.; Stiff, P.J.
Seminars in Oncology 17(2 Suppl 4: 63-67
1990
ISSN/ISBN: 0093-7754 PMID: 1692161 Document Number: 364659
The prognosis of patients with aggressive non-Hodgkin's lymphomas who fail to achieve a complete remission or who relapse following initial chemotherapy has improved dramatically in recent years. Bone marrow transplantation now provides a curative option and is the current treatment of choice. Conventional chemotherapeutic regimens are not capable of salvaging these patients; however, most patients should be treated with chemotherapy to induce a temporary remission prior to the transplantation procedure. Numerous studies are currently attempting to improve preparative chemotherapy and/or radiation therapy. Since conventional chemotherapy provides short-term palliation only, patients who are not candidates for transplantation should be entered into investigational protocols.