Chorionic villus sampling as the primary diagnostic tool in prenatal diagnosis. Should it replace genetic amniocentesis?
Doran, T.A.
Journal of Reproductive Medicine 35(10): 935-940
1990
ISSN/ISBN: 0024-7758 PMID: 2246760 Document Number: 364308
Recent studies in Canada and the United States have shown that chorionic villus sampling (CVS) is both safe and accurate, with a fetal loss rate likely slightly higher than that of amniocentesis but still at an acceptable level (1%). Although CVS may become the dominant prenatal diagnosis procedure, it is unlikely that it will completely replace amniocentesis. The two procedures are essentially complementary in the provision of prenatal diagnosis in the first and second trimesters.