Cytological patterns of primary malignant uterine fibrous histiocytoma. A case report
Torrisi, A.; Giorgino, F.; Onnis, G.L.; Minucci, D.
European Journal of Gynaecological Oncology 11(5): 343-346
1990
ISSN/ISBN: 0392-2936 PMID: 1965802 Document Number: 362806
The Authors have reported the cytological patterns of malignant primitive uterine fibrous histiocytoma of a 57 year old woman. The endometrial cytological sampling was performed by an aspiration technique using a feeding-tube; a necrotic haemorrhagic background filled with lymphocytes and polymorphonuclear leukocytes, and a mixture of highly anaplastic histiocytic and fibroblastic type cells, associated with undifferentiated small round cells, has been described. The result of the histological examination performed on the surgical specimen was the following: polymorphic malignant neoplasia characterized by spindle-like and giant plurinucleated cells, phagocytosis features, endoluminal polypoid growth, wide infiltration of the myometrium two thirds deep, vascular space invasion of the uterine wall and the hilus of the ovaries. The histological features and immunohistochemical analysis were consistent with malignant fibrous histiocytoma in the pleomorphic variety.