Piroxicam suppositories in the treatment of osteoarthritis of the knee joint

Hatori, M.; Sakurai, M.; Kokubun, S.; Rijal, K.P.

Clinical Therapeutics 12(3): 227-229

1990


ISSN/ISBN: 0149-2918
PMID: 2379226
Document Number: 361302
The subjects were 231 patients aged 16 to 75 years with osteoarthritis of the knee joint. Each patient received 20 mg of piroxicam daily as a suppository administered before sleep; 75% of the patients were treated for 14 days or longer. Over-all treatment outcome was excellent in 34% according to physicians' ratings and in 36% according to the patients' self-ratings, good in 39% and 41%, fair in 22% and 17%, and unimproved in 5% and 7%, respectively. Side effects were reported by 3% of the patients. It is concluded that treatment of osteoarthritis with piroxicam suppositories is safe and effective.

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