Cryptococcosis in acquired immunodeficiency syndrome

Lobos, T.; Acuña, G.; Espinoza, R.; León, E.

Revista Medica de Chile 118(3): 296-299

1990


ISSN/ISBN: 0034-9887
PMID: 2131511
Document Number: 361263
The diagnosis of cryptococcal infection was established in 3 patients with AIDS. Infection was meningo-encephalic in all and presented a violent outset. The chemical characteristics of the CSF were normal. Detection of cryptococcal antigen, presence of encapsulated yeast forms revealed by india-ink staining and positive cultures allowed a definitive diagnosis. Response to therapy with amphotericin B alone or in combination with 5-fluorocytosine was poor. A maintenance therapy with fluconazole is recommended.

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