A multicentre study of tenoxicam for the treatment of osteo-arthritis and rheumatoid arthritis in general practice
Langdon, C.G.; Moran, D.G.; Jamieson, V.; Spence, S.; Hill, S.A.
Journal of International Medical Research 18(6): 489-496
1990
ISSN/ISBN: 0300-0605 PMID: 2292331 Document Number: 358410
A study was undertaken to investigate the efficacy and tolerability of 20 mg/day tenoxicam given orally for 12 weeks in a general practice setting in a broad range of patients suffering from osteo-arthritis or rheumatoid arthritis. The group of 2963 patients was recruited from 252 general practices. Some patients (60%) continued treatment into the long-term phase of the trial, beyond 12 weeks, whereas other patients (31%) elected to continue treatment beyond 52 weeks. There was a reduction in the number of patients recording pain and stiffness over the course of the study. Adverse events were typical of a non-steroidal anti-flammatrory druig with no unexpected or unusual side-effects. It is concluded that tenoxicam can be recommended for use in osteo-arthritis and rheumatoid arthritis.