Occurrence of cerebrohepatorenal (Zellweger) syndrome in the Karaite community in Israel: a genetic hypothesis
Zung, A.; Mogilner, B.M.; Nissani, R.; Appelman, Z.; Gelman de Kohan, Z.
Israel Journal of Medical Sciences 26(10): 570-572
1990
ISSN/ISBN: 0021-2180 PMID: 2249933 Document Number: 358320
Two infants with the cerebrohepatorenal (Zellweger) syndrome in Karaite families are described. This syndrome has an autosomal recessive mode of inheritance with an estimated incidence of between 1:25,000 and 1:100,000 live births. In addition to a previous report of the syndrome in a Karaite family, this report raises the possibility of a high incidence of Zellweger Syndrome among the Karaites in Israel.