The influence of different copper wires on human sperm penetration into bovine cervical mucus, in vitro

Shoham, Z.; Lidor, A.; Megory, E.; Lunenfeld, B.; Blankstein, J.; Weissenberg, R.

Contraception 36(3): 327-334


ISSN/ISBN: 0010-7824
PMID: 3677677
DOI: 10.1016/0010-7824(87)90103-x
Document Number: 356651
The influence of four different copper-containing intrauterine devices (IUD) (Nova-T, Multiload, Fincoid 250 and copper-T 250) on the penetration of human sperm into bovine cervical mucus were assessed. Pooled samples of predetermined sperm concentration were suspenced in Earl's medium in which a copper IUD was previously incubated for periods between one hour to fourteen days. The mean copper concentration was determined for each of the medium containing IUD and was found to be between 284 .+-. 93 .mu.g/100ml to 392 .+-. 138 .mu.g/100ml. While there was no adverse effects on sperm motility by the copper-containing medium, there was a significant reduction in the number of sperm penetrated into the bovine cervical mucus as compared to the penetration of sperm suspended in pure Earl's medium. It therefore seems that the influence of copper on sperm penetration might be an effect on the environment of spermatozoal migration rather than by direct effect of copper on sperm motility.

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