Atypical progressive stroke syndrome associated with oral contraceptives and cigarette use

Levine, S.R.; Knake, J.E.; Young, A.B.; Levine, S.R; Knake, J.E; Young, A.B

doi:10.1161/01.str.18.2.519

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Atypical progressive stroke syndrome associated with oral contraceptives and cigarette use

Levine, S.R.; Knake, J.E.; Young, A.B.

Stroke 18(2): 519-523

1987

ISSN/ISBN: 0039-2499

PMID: 3564112

DOI: 10.1161/01.str.18.2.519

Document Number: 355980

We report a case of progressive multifocal intracranial distal arterial branch occlusive disease in a young adult who smoked heavily and used oral contraceptives. The distribution of the angiographic lesions and the associated telangiectasias and rete mirabile resemble Moya-Moya disease except for clearly absent proximal carotid arterial disease. This type of distal multifocal cerebral arterial occlusive pattern appears to be a very rare manifestation of cigarette and oral contraceptive use. The patient has remained without symptoms for greater than 3 years off oral contraceptives and cigarettes and on antiplatelet agents.