Immunoreactive circulating alpha-interferon is low in Sjögren's syndrome
Shiozawa, S.; Shiozawa, K.; Shimizu, S.; Tanaka, Y.; Morimoto, I.; Yoshihara, R.; Kuroki, Y.; Hashimoto, M.; Fujita, T.
British Journal of Rheumatology 29(1): 50-52
1990
ISSN/ISBN: 0263-7103 PMID: 2306573 Document Number: 354946
Circulating .alpha.-interferon in plasma of 26 patients with Sjogren's syndrome was 0.069 .+-. 0.034 ng/ml, a significant decrease compared with 0.119 .+-. 0.051 ng/ml for age- and sex-matched healthy subjects (P < 0.01) and compared with values previously found for healthy donors at ages 1-89 years. The results indicate the inability of Sjogren's syndrome patients to maintain circulating .alpha.-interferon.
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