Antibiotic resistance of biomaterial-adherent coagulase-negative and coagulase-positive staphylococci
Naylor, P.T.; Myrvik, Q.N.; Gristina, A.
Clinical Orthopaedics and Related Research 261: 126-133
1990
ISSN/ISBN: 0009-921X PMID: 2173986 Document Number: 354647
Whether or not bacterial populations are massively enclosed in slime, it appears that antibiotic resistance, when compared to suspension organisms, is related to surface adhesion and to the specific material of the substratum. These findings are of significance in the understanding and treatment of biomaterial-localized infections.