Diagnostic splenectomy. Apropos of 38 cases
Letoquart, J.P.; Casa, C.; Grosbois, B.; Pompilio, M.; Chaperon, J.; Lancien, G.; Jacomy, D.; Leblay, R.; Mambrini, A.
Annales de Chirurgie 44(5): 342-347
1990
ISSN/ISBN: 0003-3944 PMID: 2372195 Document Number: 353038
The authors report a retrospective study of 38 splenectomies performed as a diagnostic procedure. In the first group, the diagnosis was made by surgery: 27 cases (71.1%) included the usual large number of lymphomas. In the second group, there was no conclusion: 11 cases (28.9%), patients were younger and the spleen was lighter with a statistical significance (p less than 0.006 and p less than 0.003). Three of the 11 patients in the second group subsequently developed a malignant blood disease. Morbidity was high: out of 38 cases, 14 complications occurred in 11 patients (28.9%). One patient died on the fifty fifth postoperative day. The authors consider that splenectomy for undiagnosed splenomegaly is an effective procedure for diagnosing lymphoma, but not without risk. Indications for surgery must be carefully evaluated. It is more questionable in young, asymptomatic patients or in the case of moderate splenomegaly. After surgery, with no histologic diagnosis only a long-term survey will differentiate patients with malignant blood diseases from patients with idiopathic splenomegaly.