The evaluation of the therapeutic efficacy of auranofin in juvenile rheumatoid arthritis (the results of Soviet-American research)
Kuz'mina, N.N.; Brue, E.; Shaĭkov, A.V.; Isaeva, L.A.; Shakhbazian, I.E.; Giannini, E.; Iakovleva, A.A.; Puodzhiunene, E.P.; Vorontsov, I.M.; Astrauskene, D.S.
Terapevticheskii Arkhiv 62(5): 38-41
1990
ISSN/ISBN: 0040-3660 PMID: 2204140 Document Number: 352031
The authors describe the results of prospective multicenter Soviet-American placebo-controlled 6-month investigations concerned with assessment of the therapeutic efficacy of auranofin in juvenile rheumatoid arthritis (JRA). 231 patients with JRA were placed under observation. Auranofin was found to be slightly superior to placebo. The drug was tolerated well. It is noted that in the treatment of JRA, of importance are long (6-month) courses of non-steroidal anti-inflammatory drugs.