Androgenization in patients with polycystic ovary syndrome
Gasparov, A.S.; Pshenichnikova, T.I.; Alieva, E.A.; Fedorova, T.A.; Vetr, M.
Acta Universitatis Palackianae Olomucensis Facultatis Medicae 126: 241-246
1990
ISSN/ISBN: 0301-2514 PMID: 2151091 Document Number: 351927
150 infertile patients with the polycystic ovary syndrome (PCOS), aged 19 to 36 years, have been investigated. PCOS was diagnosed on the basis of clinical symptoms, and the diagnosis was verified by laparoscopy, followed by histologic investigation of ovarian biopsy specimens. Hirsutism was found in 43% of the patients, while hair growth was marginal in 30% and normal in 27%. Testosterone (T) levels were increased significantly (p less than 0.05) in the PCOS patients with hirsutism or marginal hair growth, as compared to reference values.