The morphological findings in the myometrial arteries and in the placenta with reference to the age of primaparae
Popov, I.; Ganchev, S.; Bakŭrdzhiev, G.
Akusherstvo i Ginekologiia 29(4): 20-23
1990
ISSN/ISBN: 0324-0959 PMID: 2267976 Document Number: 351084
The authors investigate primiparous women at various ages, searching for eventual changes in uterine blood vessels and in the placenta, which eventually could have unfavourable effect on the fetus. The study established progressive thickening due to fibrosis of the muscular layer of the myometrial arteries (in reduction of smooth muscular elements) as well as delay of maturation and differentiation of placental villi with advancement of age of the pregnant woman. These phenomena independently could be the cause for more frequent unfavourable outcome of pregnancy in elderly pregnant women.