Bleomycin-induced pulmonary toxicity
Jules-Elysee, K.; White, D.A.
Clinics in Chest Medicine 11(1): 1-20
1990
ISSN/ISBN: 0272-5231 PMID: 1691067 Document Number: 350866
Bleomycin is recognized to cause an interstitial pneumonitis that can lead to fibrosis. Although its occurrence may be sporadic, some factors may increase the risk of such a pulmonary reaction. In this article the clinical setting and presentation, radiographic manifestations, pathologic findings, and the prognosis of bleomycin-induced interstitial fibrosis are described. Additionally, the role of pulmonary function tests in monitoring patients for toxicity is discussed.