Drug-associated aplastic anemia in dogs: eight cases (1984-1988)
Weiss, D.J.; Klausner, J.S.
Journal of the American Veterinary Medical Association 196(3): 472-475
1990
ISSN/ISBN: 0003-1488 PMID: 2298681 Document Number: 350122
Records of 8 dogs with drug-associated aplastic anemia were reviewed. Drugs suspected as being causative included estradiol cyclopentylpropionate (3 dogs), phenylbutazone (2 dogs), meclofenamic acid (1 dog), trimethoprim-sulfadiazine and fenbendazole (1 dog), and quinidine (1 dog). Five of the dogs died or were euthanatized. One dog with estrogen-associated aplasia recovered after prolonged treatment. The dogs with trimethoprim-sulfadiazine and quinidine-associated marrow aplasia recovered promptly after treatment was discontinued.