Angiotrophic lymphoma. Presentation in uterine vessels with cytogenetic studies
Davey, D.D.; Munn, R.; Smith, L.W.; Cibull, M.L.
Archives of Pathology and Laboratory Medicine 114(8): 879-882
1990
ISSN/ISBN: 0003-9985 PMID: 2375663 Document Number: 350024
An unusual case of angiotrophic lymphoma diagnosed initially in the uterus is described. Immunohistochemical studies documented the intravascular tumor cells in the myometrium to be of B lymphocytic origin. The patient's bone marrow was hypercellular, and cytogenetic studies of the aspirate revealed a subpopulation of cells with multiple clonal chromosomal abnormalities. To our knowledge, this is the first case to document abnormal cytogenetic findings in this uncommon malignancy.