In vitro enzyme inhibitory and in vivo cardioprotective activities of hibiscus (Hibiscus sabdariffa L.)

Jonadet, M.; Bastide, J.; Bastide, P.; Boyer, B.; Carnat, A.P.; Lamaison, J.L.; Jonadet, M; Bastide, J; Bastide, P; Boyer, B; Carnat, A.P; Lamaison, J.L

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In vitro enzyme inhibitory and in vivo cardioprotective activities of hibiscus (Hibiscus sabdariffa L.)

Jonadet, M.; Bastide, J.; Bastide, P.; Boyer, B.; Carnat, A.P.; Lamaison, J.L.

Journal de Pharmacie de Belgique 45(2): 120-124

1990

ISSN/ISBN: 0047-2166

PMID: 2355305

Document Number: 348954

A crude hydroalcoholic extract from Hibiscus sabdariffa L. calyces showed in vitro an appreciable enzyme-inhibiting activity towards the Angiotensin I Converting Enzyme (ACE), attributable to flavones, but weak inhibiting activities towards elastase, trypsin and alpha-chymotrypsin. The angioprotective activity in vivo, also important, was due to flavones and anthocyanins.