In vitro drug susceptibility of Mycobacterium other than tubercle bacilli
Imwidthaya, P.; Komolpis, P.; Suthiravitayavaniz, K.; Rienthong, S.
Journal of the Medical Association of Thailand 73(8): 438-442
1990
ISSN/ISBN: 0125-2208 PMID: 2262746 Document Number: 348559
MOTT were isolated from clinical specimens from the Division of Mycobacteriology, Department of Microbiology, Siriraj Hospital, Mahidol University, and also from natural sources, namely water and soil in the Bangkok [Thailand] area from January to December, 1987. The strains isolated were as follows: 30 Mycobacterium fortuitum fortuitum, 5 M. fortuitum peregrinum 3 M. fortuitum 3 rd. biovariant complex, 3 M. chelonae chelonae, 7 M. chelonae abscessus. Of these, 5 strains were isolated from clinical specimens and the other 43 were from the environment. The pattern of drug susceptibility to antituberculous and antimicrobial agents revealed that they were resistant to antituberculous agents but susceptible to aminoglycosides (which contain a central ring of 2-deoxystreptamine) such as amikacin (83% of cultures), netilmicin (83%), gentamicin (77%) and kanamycin (75%). Some strains were sensitive to tetracyclines (35%), but all were resistant to penicillins and cephalosporins.