Dipyridamole-exercise association in the diagnosis of ischemic heart disease

Zdrenghea, D.; Beudean, M.; Predescu, D.; Bogdan, E.; Ossian, V.

Medecine Interne 28(3): 235-240

1990


ISSN/ISBN: 0377-1202
PMID: 2092394
Document Number: 348020
Dipyridamole-exercise ECG test (DET) was found to present a greater sensitivity than exercise or dipyridamole ECG test alone in detecting ischemic heart disease (IHD). A group of 39 patients with probable IHD and negative exercise test was investigated by i.v. dipyridamole administration. Eight subjects presented significant ECG changes. The remaining 31 subjects were submitted to a new exercise test which became positive in 7 subjects (23%). The percentage increases to 38% by taking into account the positive dipyridamole test. The authors concluded that DET substantially improve the diagnosis of myocardial ischemia in subjects with probable IHD and negative exercise test.

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