Remission induction treatment in adults with acute myeloid leukemia. 8-year experience with 2 successive protocols
Del Potro, E.; Díaz Mediavilla, J.; Martínez, R.; Alvarez, A.; Krsnik, I.; Guerra, J.L.; Llorente, L.; López, J.C.; Díaz Morfa, M.; Villegas, A.
Medicina Clinica 92(16): 601-604
1989
ISSN/ISBN: 0025-7753 PMID: 2747321 Document Number: 346888
We report our eight year experience remission induction therapy in adult patients with acute myeloblastic leukemia. Overall 67 patients were treated, with a mean age of 43.3 years (range 15-75). Two treatment protocols were used. Complete remission (CR) was achieved in 23 patients of 39 receiving protocol A (58%). The 28 last patients were treated with the more aggressive protocol B, and CR was achieved in 23 patients (82%). CR was achieved in 68% of the overall group. The most outstanding predictive factors were age above 30 years, and M-5 morphology as indicating a poor prognosis.