The eosinophil--the human blood cell superaffined to endotoxin
Iakovlev, M.I.; Kubatiev, A.A.; Krupnik, A.N.; Bondarenko, V.M.; Sudzhan, E.V.
Biulleten' Eksperimental'noi Biologii i Meditsiny 107(6): 765-766
1989
ISSN/ISBN: 0365-9615 PMID: 2676009 Document Number: 344627
With the help of immunofluorescent diagnostic system (specific immunoglobulins against glycolipid of S. minnesota Re-595) has been shown to permit the detection of endotoxin into eosinophil. Statistically significant differences in the occurrence of endotoxin in eosinophils of patients and healthy persons have been revealed. These data allow us to suppose that eosinophils are superaffined endotoxin-interaction cells of the human blood. Eosinopenia may be taken into account as an indirect marker of systemic LPS O-antigen mediated endotoxinemia.