Biologic theories of aging

Goldstein, S.; Gallo, J.J.; Reichel, W.

American Family Physician 40(3): 195-200

1989


ISSN/ISBN: 0002-838X
PMID: 2773758
Document Number: 344258
Many theories have been proposed to explain aging. Currently, the most important theories include genetic control, deterioration of the immune system, somatic mutation, accumulated damage by free radicals, cross-linkage of macromolecules, and metabolic causes. While no single theory accounts for all of the observations about aging, recent research suggests that the primary process is under genetic control, with contributions from environmental factors.

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