Treatment of ectopic pregnancy with prostaglandin E2
Ribic-Pucelj, M.; Novak-Antolic, Z.; Vrhovec, I.
Clinical and Experimental Obstetrics and Gynecology 16(4): 106-109
1989
ISSN/ISBN: 0390-6663 PMID: 2483363 Document Number: 344220
In 10 patients the treatment of ectopic pregnancy consisted of the use of 0.75 to 2.25 mg of prostaglandin E2 (Prostin E2, 1 mg/ml, Upjohn). In 8 patients PGE2 was injected in the tubal wall under laparoscopic control, in 2 under the control of vaginal ultrasound probe. The effect of the treatment was controlled by serial determinations of serum beta HCG. In 8 patients with PGE2 injected laparoscopically, negativization of beta HCG took place in 14 +/- 8 days which meant successful treatment of ectopic pregnancy. For persistently elevated beta HCG concentrations in both patients with PGE2 applied under the ultrasound control, laparotomy had to be performed.