Transdermal delivery of drugs by iontophoresis: a review
Singh, J.; Roberts, M.S.
Drug Design and Delivery 4(1): 1-12
1989
ISSN/ISBN: 0884-2884 PMID: 2673280 Document Number: 344077
The advantages and limitations, theory, and factors in the use of electric current to deliver drugs across the skin are discussed. Application of the technique in the delivery of local anaesthetics, antibiotics/antibacterials, mydriatics, vinca alkaloids, non-electrolytes, biogenic amines, peptides, and other agents is reviewed. It is concluded that the method alone, or in combination with phonophoresis (delivery via ultrasonic perturbation), offers considerable scope in the transdermal delivery of drugs.