Hypogastric arteriography prior to continuous infusion of malignant tumors of the uterine cervix and vagina. A preliminary report
Zeit, P.R.; Hughes, C.R.; Cahill, J.J.; Hamilton, J.G.
Cleveland Clinic Quarterly 27: 119-124
1960
ISSN/ISBN: 0009-8787 PMID: 13788112 Document Number: 343603
Four anatomic requirements for a technically successful continuous infusion of a malignant tumor in any part of the body are: (1) the one or 2 arteries selected for infusion must deliver most of their blood to the region of the tumor; (2) most of the blood supply of the tumor itself must come from these arteries; (3) the vessels must be accessible and of adequate size to be catheterized easily; (4) sacrifice of the arteries must be possible, if necessary, without serious damage to normal tissues. The anatomic arrangement of the hypogastric arteries in the human female, as demonstrated by arteriograms, is such that the above 4 requirements can be fulfilled for infusion of malignant tumors of the uterine cervix and vagina. Ligation of the superior and inferior gluteal arteries diverts most of the blood flow in the hypogastric artery to the uterine, internal pudendal, middle hemorrhoidal, and vaginal arteries. The technic of hypogastric arteriography has been briefly described. In the 9 patients reported by the authors there were no undesirable effects or complications arising from the procedure.