Fish oil: clinical application possibilities
Steiner, A.; Greminger, P.; Vetter, W.
Schweizerische Rundschau für Medizin Praxis 78(41): 1126-1131
1989
ISSN/ISBN: 1013-2058 PMID: 2678376 Document Number: 343032
Current interest in fish-oil stems in part from epidemiologic evidence gathered in eskimos. Due to a high proportion of fish in their diet eskimos have a low incidence in cardiovascular mortality. The active principle in fish-diet are n-3-fatty acids. These modulate prostaglandin and leukotriene metabolism. Numerous studies have been undertaken to demonstrate clinical usefulness. Current interests focus on lipid lowering, inhibition of hemostasis and antihypertensive actions. Furthermore antiinflammatory and immunologic effects as well as uses in oncology are discussed.