Thrombocytopenia in a patient with hemophilia and HIV infection treated with intravenous immunoglobulin and splenectomy
Rozmysłowicz, T.; Ziemski, J.M.; Rudowski, W.; Lopaciuk, S.
Przeglad Dermatologiczny 76(4): 302-307
1989
ISSN/ISBN: 0033-2526 PMID: 2517146 Document Number: 342459
In a patient with haemophilia B who had developed immune thrombocytopenia following HIV infection, high doses of intravenous immunoglobulin were administered. The therapy brought about only a temporary rise in platelet counts. No beneficial effects were also obtained during a 3-month treatment with corticosteroids. Since there was no response to the conservative therapy, the patient was splenectomized under the cover of factor IX concentrate and the surgical procedure resulted in a complete remission of the thrombocytopenia.