Partial lipodystrophy and membranoproliferative glomerulonephritis. Apropos of a case
Martínez Debora, M.J.; Vázquez Martul, M.; Ecija Peiró, J.L.; González Pérez, J.; Lirio Rodríguez, J.; González Mediero, I.
Anales Espanoles de Pediatria 30(6): 499-502
1989
ISSN/ISBN: 0302-4342 PMID: 2679278 Document Number: 341493
We have studied a girl seven and a half years old with a renal disease manifested by proteinuria and nephrotic syndrome combined with initial macroscopic hematuria normal blood pressure and persistent depression of the complement C3 levels with the complement activating gamma globulin (C3 Nef) present in serum. The anatomopathological study showed findings of membranoproliferative glomerulonephritis type II with intramembranous deposit (dense deposit disease). An unusual association with partial lipodystrophy was present in this case. A follow-up of five years, and a few considerations about etiopathogenic theories were presented.