Restriction fragment length polymorphism analysis of class II genes and canine bone marrow transplantation: correlation with mixed lymphocyte reactivity

Williamson, P.; Byrne, J.T.; Taylor, R.M.; Stewart, G.J.

Transplantation Proceedings 21(5): 3824-3825

1989


ISSN/ISBN: 0041-1345
PMID: 2573186
Document Number: 340972
Genomic DNA from English Springer Spaniel dogs carrying the recessive allele for fucosidosis (a disorder that can be corrected by bone marrow transplantation), and representing different mixed lymphocyte reaction (MRL) types, hybridized with human cDNA probes for the DRB and DQB genes. Restriction fragment length polymorphisms were found which correlated with MLR type.

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