A thioridazine-dihydroergotoxine combination in the treatment of senile pruritus
Polenghi, M.; Colombo, M.D.; Barcella, M.L.; Perego, M.
Giornale Italiano di Dermatologia e Venereologia Organo Ufficiale Societa Italiana di Dermatologia e Sifilografia 124(9): Li-Liii
1989
ISSN/ISBN: 0392-0488 PMID: 2635137 Document Number: 339299
Senile itching, a peculiar clinical situation consisting of a cutaneous senile involution associated with a relevant neurogenic component, still keeps being a difficult therapeutic problem. For the purpose, a clinical trial, carried out with a combination of thioridazine and dihydroergotoxine on 19 patients carriers of the affection, could show a relevant decrease in all parameters assessed, ie itching, muscle tension and skin temperature measured by biofeedback. The combination also showed a good tolerance.