Single-dose pharmacokinetics of flurbiprofen granules and tablets in healthy volunteers
Benvenuti, C.; Gambaro, V.; Lodi, F.; Scaroni, C.; Bandi, G.; Valenti, M.
International Journal of Clinical Pharmacology Therapy and Toxicology 27(7): 334-337
1989
ISSN/ISBN: 0174-4879 PMID: 2777421 Document Number: 339046
The bioavailability of granules and tablet flurbiprofen in 100 mg single dose was crossover compared in 6 healthy volunteers (mean aged 26.8 years). The granules showed an earlier peaktime and a lower maximum concentration than the tablet. Area under the curve and half-time in terminal phase were similar, with the granule relative bioavailability of 0.98.
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