Specificity of the location of human chromosomes in the nucleus of a moving cell
Gar'kavtsev, I.V.; Tsvetkova, T.G.; Terekhov, S.M.; Aleksandrov, I.A.; Mitkevich, S.P.
Biulleten' Eksperimental'noi Biologii i Meditsiny 108(10): 479-481
1989
ISSN/ISBN: 0365-9615 PMID: 2597766 Document Number: 338849
Data are presented on the distribution of centromeric heterochromatin of the human X-chromosome in the interphase nucleus of a moving cell. The in situ hybridization made it possible to obtain some results leading to the following conclusions: in moving fibroblasts centromeric heterochromatin of the X-chromosome is located in end regions of the interphase nucleus; there was no preferential localization noted of the centromeric region of the X-chromosome in the front or back areas of the nucleus as to the direction of the movement.