Congenital ependymoma. Case report and immunohistochemical studies
Heye, N.; Iglesias, J.; Huber, S.; Lobeck, H.
Zentralblatt für Allgemeine Pathologie U. Pathologische Anatomie 135(1): 43-49
1989
ISSN/ISBN: 0044-4030 PMID: 2467463 Document Number: 338564
Reported in this paper is a congenital ependymoma in an 23-week old foetus. The neoplasm was well vascularised and contained typical ependymal rosettes. The tumour cells did not react with GFAP-antiserum. They reacted weakly with neuron-specific enolase and vimentin and exhibited strong antigenicity with S-100-protein-antiserum. Cytokeratin antigen was recordable from some tumour cells. The tumour was sufficiently mature for classification as ependymoma. Immunohistochemical findings suggested possible ectodermal origin of the tumour cells.