Disorders of external respiration and oxygen transport and utilization in stress
Meerson, F.Z.; Miniaĭlenko, T.D.; Pozharov, V.P.; Seredenko, M.M.
Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 1989(6): 20-26
1989
ISSN/ISBN: 0031-2991 PMID: 2628875 Document Number: 337801
A specific hypoxic condition characterized by a combination of signs of hypoxic, circulatory, and primary tissue hypoxia develops in rats after 6-hour immobilization stress. Post-stress hypoxia is assompanied with accumulation of lactate, decompensated metabolic acidosis, and activation of lipid peroxidation processes in the blood and tissues. Besides, a complex of changes of external respiration, its regulation and biomechanics, inhibition of pulmonary gas exchange is encountered after the stress, which is linked with the development of specific stress damage to the lungs which can be characterized as the stress lung syndrome.