Late results of the treatment of acute granulocytic leukemia in adults

Perilov, A.A.; Volkova, M.A.; Frenkel', M.A.

Terapevticheskii Arkhiv 61(7): 8-11

1989


ISSN/ISBN: 0040-3660
PMID: 2588148
Document Number: 337784
Eighteen patients with acute granulocytic leukemia (MI-1, M2-10, M3-1 and M4-6) underwent AdOAP treatment. Complete remissions were achieved in 10 out of the 18 patients (55.6%), 3 patients proved resistant, 5 had died prior to recovery of normal hemopoiesis. Three lethal cases are attributed to the results of the therapy complications. Median duration of complete remissions reached 17.5 months. Two patients have been in remission over 3 years. Reduced duration or intensity of the induction therapy failed to diminish frequency of lethal complications due to progressive cytopenia.

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