Study and application of the DNA pattern in oncology
De Aretxabala, X.; Roa, I.; Araya, J.C.; Roa, J.C.
Revista Medica de Chile 117(9): 1044-1048
1989
ISSN/ISBN: 0034-9887 PMID: 2519471 Document Number: 337755
Abnormalities of DNA content are commonly observed in malignant tumors. Clinically relevant information may be obtained given the ease with which DNA pattern can be studied. Flux cytometry and photocytometry are the methods commonly used and both measure the emission of fluorescence after staining the nucleus. ADN pattern has been found to be related to prognosis in many tumors. Also, precancerous lesions and tumor heterogeneity can be analyzed by this technique.