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Evaluation of the complement split product C3dg in synovial fluid as a possible diagnostic guide in inflammatory arthropathies

Michel, B.A.; Schlumpf, U.; Simmler, F.

Journal of Rheumatology 16(9): 1201-1204

1989

ISSN/ISBN: 0315-162X
PMID: 2810276
Document Number: 337359
Analyses of C3 split products with C3d specificity (C3dg) were performed in 157 synovial fluids (SF) of 129 patients with various known joint diseases. Considerable overlap between all inflammatory infectious, and crystal induced disease categories confines the value of such measurements as a diagnostic guide to only a few clinical situations. In seronegative as well as in seropositive rheumatoid arthritis no correlation between SF C3d levels and erythrocyte sedimentation rate could be found.

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