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Concentration of kininogens and low molecular kininogen antigen in plasma of pregnant rabbits and newborn progeny in health and following intravenous infusion of purified thrombin

Kleniewski, J.; Hagel-Lewicka, E.

Polski Tygodnik Lekarski 44(10-11): 257-261

1989

ISSN/ISBN: 0032-3756
PMID: 2813157
Document Number: 336910
High levels of trypsin-releasing kinin and low molecular plasma kininogen antigen were detected in plasma of pregnant female rabbits. Respective values in plasma of their new born progeny was 2.7 times lower than that in maternal plasma. Intravenous infusion of the highly purified bovine thrombin administered to pregnant female rabbits markedly decreased plasma fibrinogen platelet count and increased fibrinogen/fibrin degradation products in blood serum. A marked decrease of trypsin-releasing kinin plasma levels accompanied these changes. No changes in the kininogen antigen levels were seen during the same experiments. Thrombin infusions administered to pregnant female rabbits did not produce measurable changes in trypsin-releasing kinin levels and plasma low molecular kininogen antigen in the progeny obtained for the investigations with the aid of cesarean section.

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Hamberg, U.; Syvanen, A.C.; Karkkainen, T. 1983: Immunoassay of molecular forms of human plasma kininogen and detection of low Mr fragments of kininogen by means of a conformation-dependent antigenic determinant Advances in Experimental Medicine and Biology 156: 175-182
Paradowski, A.; Miazgowski, T.; Ogonowski, J.; Cretti, A. 1983: The effect of prostaglandin synthetase inhibitor on pressor reaction during intravenous infusion of angiotensin II in pregnant rabbits Ginekologia Polska 54(7): 445-451
Song, L.; Wang, L.; Jiang, X. 2011: Study on pharmacokinetics of lansoprozole in concentration of blood plasma healthy volunteers intravenous infusion by improved HPLC Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 28(2): 300-304
Verma, P.S.; Adams, R.G.; Miller, R.L. 1983: Reduced plasma kininogen concentration during sickle cell crisis Research Communications in Chemical Pathology and Pharmacology 41(2): 313-322
Scicli, A.G.; Mindroiu, T.; Scicli, G.; Carretero, O.A. 1982: Blood kinins, their concentration in normal subjects and in patients with congenital deficiency in plasma prekallikrein and kininogen Journal of Laboratory and Clinical Medicine 100(1): 81-93
Nakamura, K.; Akutsu, S.; Matsumoto, H.; Samura, K.; Nakata, Y.; Asano, M.; Hirata, A.; Ishikawa, H.; Matsuzaki, M. 1982: Toxicological study of amikacin following intravenous drip infusion. 1. Acute toxicity in rats, rabbits and dogs, and subacute toxicity in rabbits Japanese Journal of Antibiotics 35(8): 2048-2067
Momi, S.; Nasimi, M.; Colucci, M.; Nenci, G.G.; Gresele, P. 2001: Low molecular weight heparins prevent thrombin-induced thrombo-embolism in mice despite low anti-thrombin activity. Evidence that the inhibition of feed-back activation of thrombin generation confers safety advantages over direct thrombin inhibition Haematologica 86(3): 297-302
Tsai, T.H.; Chou, C.J.; Chen, C.F. 1994: Disposition of magnolol after intravenous bolus and infusion in rabbits Drug Metabolism and Disposition: the Biological Fate of Chemicals 22(4): 518-521
Spitzer, E.; Grosse, R. 1987: EGF receptors on plasma membranes purified from bovine mammary gland of lactating and pregnant animals Biochemistry International 14(4): 581-588
Ueshima, S.; Silence, K.; Collen, D.; Lijnen, H.R. 1993: Molecular conversions of recombinant staphylokinase during plasminogen activation in purified systems and in human plasma Thrombosis and Haemostasis 70(3): 495-499
Matsueda, R.; Umeyama, H.; Puri, R.N.; Bradford, H.N.; Colman, R.W. 1994: Design and synthesis of a kininogen-based selective inhibitor of thrombin-induced platelet aggregation Peptide Research 7(1): 32-35
Sakata, H. 1985: Pulmonary thromboembolism of rabbits receiving an intravenous single infusion of autologous thrombus with special reference to the pathogenesis of initial lesions Nihon Kyobu Shikkan Gakkai Zasshi 23(10): 1144-1157
Oda, A.; Aoki, A.; Ozaki, T.; Unno, K.; Nagai, N. 1972: Behavior of hydroxyethyl starch in the plasma and urine of man following intravenous infusion Masui. Japanese Journal of Anesthesiology 21(8): 747-753
Perez, E.A.; Lembersky, B.; Kaywin, P.; Kalman, L.; Yocom, K.; Friedman, C. 1998: Comparable safety and antiemetic efficacy of a brief (30-second bolus) intravenous granisetron infusion and a standard (15-minute) intravenous ondansetron infusion in breast cancer patients receiving moderately emetogenic chemotherapy Cancer Journal from Scientific American 4(1): 52-58
Bortolotti, A.; Castelli, D.; Bonati, M. 1989: Hematology and serum chemistry values of adult, pregnant and newborn New Zealand rabbits (Oryctolagus cuniculus) Laboratory Animal Science 39(5): 437-439
Walsh, T.J.; Lee, J.W.; Bacher, J.; Kelly, P.; Pizzo, P.A. 1992: Continuous intravenous infusion and simultaneous pharmacokinetic monitoring in ambulatory rabbits with a programmable micropump and dual subcutaneous Silastic central venous catheters Laboratory Animal Science 42(3): 286-292
Iliev, B.; Stambolov, B.; Khristov, M. 1993: The prevalence of the HBsAg carrier state among pregnant women and its effect on newborn infants. V. A follow-up of the processes of HBsAg clearance in pregnant women discovered as antigen carriers Akusherstvo i Ginekologiia 32(1): 14-16
Vecchiet, L.; Dolce, V.; Di Luzio, V.; Fini, F. 1974: Data on the tissular algogenic activity of the plasma after muscular work. 3. Determination of plasma kininogen Bollettino della Societa Italiana di Biologia Sperimentale 49(13): 773-778
Nabukhotnyĭ, T.K.; Pavliuk, V.P. 1986: Progesterone concentration of the plasma of newborn infants Pediatriia 11: 77-78
Colman, R.W.; Williams, M. 1992: Contributions of Mayme Williams to the elucidation of the multiple functions of plasma kininogens Thrombosis and Haemostasis 68(2): 99-101