Molecular mechanisms of protective reactions of the body: time scale, specificity scale
Troitskiĭ, G.V.
Ukrainskii Biokhimicheskii Zhurnal 61(5): 3-15
1989
ISSN/ISBN: 0201-8470 PMID: 2686138 Document Number: 335751
Heterogeneous conformation transition (HCT) peculiar to proteins is the earliest protection of the organism from poisons, toxins and pathological metabolites, HCT is conjugated with the biosynthesis of heat shock proteins (HSP), glycosylation of modified albumin and with an increase in the biosynthesis of soluble lectins, acute phase reactants (APR). All phases except for HCT are regulated at different levels of the protein biosynthesis. Their individual time corresponds to the evolution stages.