Pyogenic liver abscess. Review of 33 cases

Comas Casanova, P.; Vargas Blasco, V.; Almirante Grágera, B.; González Fernández, A.; García Sureda, D.; Esteban Mur, R.; Guardia Massó, J.

Revista Clinica Espanola 185(5): 225-229

1989


ISSN/ISBN: 0014-2565
PMID: 2608979
Document Number: 335134
Thirty three cases of pyogenic liver abscess, (24 single and 9 multiple), diagnosed in our department during the past 6 years, were reviewed. Mean patient age was 54 years with a male predominance over females (1.5:1). The most frequently encountered underlying pathology was bile duct disease (33%), followed by previous liver disease (21%). Causal pathology could not be found in 4 cases (12%). The most frequent sign was fever (76%). Diagnosis was made by clinical picture and complementary exam (ecography, CT scan and hepatic gammagraphy) in 29 cases (88%). Blood and plus cultures were positive in 47 and 67% of cases respectively. Thirty nine per cent of microbial abscesses were polymicrobial. Escherichia coli and Streptococcus milleri were the most frequently isolated. No micro-organism were identified in 5 cases (15%). Antibiotic treatment was given to 33 patients. Surgical drainage was performed in 24 cases and percutaneous drainage in 7 patients. Two patients received antibiotics exclusively. Five patients died (15%), three of whom had a multiple abscess (33%) and the other two had a single abscess (8%). The efficacy of percutaneous drainage for diagnosis and treatment is analyzed reviewing recent literature.

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