Serum apolipoprotein and lipoprotein levels in patients with diabetes mellitus type 2
Gosiewska, A.; Zarzycki, W.; Depta, K.; Składanek, J.; Kinalski, M.; Lopaczyński, W.
Wiadomosci Lekarskie 42(7): 436-440
1989
ISSN/ISBN: 0043-5147 PMID: 2629300 Document Number: 334446
Lipid disturbances were evaluated in type II diabetes comparing the results of determinations of total cholesterol and HDL-cholesterol with apolipoprotein A and B levels. The study was carried out in 32 diabetics with type II disease with mean duration 7 +/- 9 years, 15 males and 17 females, and in 30 controls. In all cases postprandial glycaemia, haemoglobin A1C, total cholesterol concentration (by the Liebermann-Burchardt method), HDL-cholesterol (by the Błaszczyszyn method), triglycerides (by the enzymatic method), an apolipoprotein A and B (by Mancini radial immunodiffusion method using a Bio-Merieux kit) were determined. A significant correlation was demonstrated between the concentrations of cholesterol and apolipoprotein A, on the one hand, and blood glucose level, on the other, and apolipoprotein A was found to be a better indicator of lipid disturbances in the aspect of diabetes control then apolipoprotein B. The latter was a better indicator of lipid disturbances in diabetes connected with obesity, than total cholesterol.